Integrasi Pengukuran Laktat Dengan Pemantauan Intrapartum Untuk Deteksi Dini Persalinan Lama: Narrative Review
DOI:
https://doi.org/10.30606/jmn.v11i2.4134Keywords:
Asam laktat, Persalinan lama, Air ketubanAbstract
Penelitian ini dilatarbelakangi oleh realitas bahwa persalinan lama masih kerap terlambat terdeteksi karena penilaian kemajuan persalinan sangat bergantung pada indikator klinis yang definisinya beragam dan interpretasinya dapat berbeda antar fasilitas, sehingga berisiko memicu intervensi yang terlalu cepat atau terlalu lambat. Tujuan penelitian ini adalah mengetahui bahwa asam laktat efektif dalam menentukan persalinan lama sebagai bentuk deteksi dini, khususnya melalui pengukuran pada air ketuban dan darah. Metode yang digunakan adalah penelitian kepustakaan dengan pendekatan Narrative Literature Review (NLR), yaitu menyusun tinjauan pustaka naratif untuk memberikan gambaran luas dan mendalam tentang topik berdasarkan penelitian yang tersedia, dengan pemilihan literatur yang bersifat fleksibel namun tetap relevan terhadap kata kunci persalinan lama, air ketuban, dan asam laktat. Data penelitian berupa temuan-temuan dari literatur yang menggambarkan variasi definisi persalinan lama, karakteristik air ketuban sebagai medium biologis dan klinis intrapartum, serta pola pelaporan laktat sebagai indikator metabolik yang dapat diukur dan dikaitkan dengan progres persalinan maupun luaran persalinan tertentu. Kesimpulan penelitian ini menunjukkan bahwa asam laktat berpotensi efektif sebagai biomarker pendukung untuk menentukan persalinan lama secara lebih dini, terutama ketika diintegrasikan dengan pemantauan kemajuan persalinan, sehingga dapat memperkuat ketepatan pengambilan keputusan intrapartum secara lebih objektif dan kontekstual
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Ayenew, A. A., & Zewdu, B. F. (2020). Partograph Utilization as a Decision-Making Tool and Associated Factors Among Obstetric Care Providers in Ethiopia: a Systematic Review and Meta-Analysis. Systematic Reviews, 9(251). https://doi.org/10.1186/s13643-020-01505-4
Bakhsh, H., Alenizy, H., Alenazi, S., Alnasser, S., Alanazi, N., Alsowinea, M., Alharbi, L., & Alfaifi, B. (2021). Amniotic fluid disorders and the effects on prenatal outcome: a retrospective cohort study. BMC Pregnancy and Childbirth, 21(1). https://doi.org/10.1186/s12884-021-03549-3
Brooks, G. A., Curl, C. C., Leija, R. G., Osmond, A. D., Duong, J. J., & Arevalo, J. A. (2022). Tracing the lactate shuttle to the mitochondrial reticulum. In Experimental and Molecular Medicine (Vol. 54, Issue 9, pp. 1332–1347). Springer Nature. https://doi.org/10.1038/s12276-022-00802-3
Brüggemann, C., Carlhäll, S., Grundström, H., & Blomberg, M. (2022). Labor dystocia and oxytocin augmentation before or after six centimeters cervical dilatation, in nulliparous women with spontaneous labor, in relation to mode of birth. BMC Pregnancy and Childbirth, 22(1). https://doi.org/10.1186/s12884-022-04710-2
Chen, L., Luo, Y., Chen, Y., Wang, L., Wang, X., Zhang, G., Ji, K., & Liu, H. (2022). Time Course Analysis of Transcriptome in Human Myometrium Depending on Labor Duration and Correlating With Postpartum Blood Loss. Frontiers in Genetics, 13. https://doi.org/10.3389/fgene.2022.812105
De Kroon, R. R., de Baat, T., Senger, S., & van Weissenbruch, M. M. (2022). Amniotic Fluid: A Perspective on Promising Advances in the Prevention and Treatment of Necrotizing Enterocolitis. In Frontiers in Pediatrics (Vol. 10). Frontiers Media S.A. https://doi.org/10.3389/fped.2022.859805
Desta, M., Mekonen, Z., Alemu, A. A., Demelash, M., Getaneh, T., Bazezew, Y., Kassa, G. M., & Wakgari, N. (2022). Determinants of obstructed labour and its adverse outcomes among women who gave birth in Hawassa University Referral Hospital: A case-control study. PLoS ONE, 17(6), 1–14. https://doi.org/10.1371/journal.pone.0268938
Dockree, S., O’Sullivan, J., Shine, B., James, T., & Vatish, M. (2022). How should we interpret lactate in labour? A reference study. BJOG: An International Journal of Obstetrics and Gynaecology, 129(13), 2150–2156. https://doi.org/10.1111/1471-0528.17264
Gates, M., Gates, A., Guitard, S., Pollock, M., & Hartling, L. (2020). Guidance for overviews of reviews continues to accumulate, but important challenges remain: a scoping review. Systematic Reviews, 9(1). https://doi.org/10.1186/s13643-020-01509-0
Jochumsen, S., Hegaard, H. K., Rode, L., Jørgensen, K. J., & Nathan, N. O. (2023). Maternal factors associated with labor dystocia in low-risk nulliparous women. A systematic review and meta-analysis. In Sexual and Reproductive Healthcare (Vol. 36). Elsevier B.V. https://doi.org/10.1016/j.srhc.2023.100855
Karasin, Z. T., Çift, T., & Karaşin, S. S. (2022). The evaluation of amniotic fluid lactate level in predicting cesarean delivery and early neonatal acidemia. Sri Lanka Journal of Obstetrics and Gynaecology, 44(1), 7–15. https://doi.org/10.4038/sljog.v44i1.8026
Karlsson, S., Patavoukas, E., Sterpu, I., Wallstrom, T., & Wiberg-Itzel, E. (2022). Body mass index and labor outcome associated with the level of amniotic fluid lactate. A cross-sectional study of women with labor dystocia. Journal of Maternal-Fetal and Neonatal Medicine, 35(25), 8521–8529. https://doi.org/10.1080/14767058.2021.1986811
Kissler, K., & Hurt, K. J. (2023). The Pathophysiology of Labor Dystocia: Theme with Variations. In Reproductive Sciences (Vol. 30, Issue 3, pp. 729–742). Institute for Ionics. https://doi.org/10.1007/s43032-022-01018-6
Kleinmann, W., Zofkie, A. C., McIntire, D. D., & Adhikari, E. H. (2023). Lactate levels increase significantly in the second stage of spontaneous and induced labor. American Journal of Obstetrics and Gynecology, 228(1), S410. https://doi.org/10.1016/j.ajog.2022.11.714
Kraus, S., Breier, M., Lim, W. M., Dabic, M., Kumar, S., Kanbach, D., Mukherjee, D., Corvello, V., Pinero-Chousa, J., Liguori, E., Palacios-Marques, D., Schiavone, F., Ferraries, A., Fernandes, C., & Ferreira, J. J. (2022). Literature Review as Independent Studies: Guidelines For Academic Practice. Review of Managerial Science, 16, 2577–2595. https://doi.org/.1007/s11846-022-00588-8
Li, X., Yang, Y., Zhang, B., Lin, X., Fu, X., An, Y., Zou, Y., Wang, J. X., Wang, Z., & Yu, T. (2022). Lactate metabolism in human health and disease. In Signal Transduction and Targeted Therapy (Vol. 7, Issue 1). Springer Nature. https://doi.org/10.1038/s41392-022-01151-3
Liu, Y., Gong, Q., Yuan, Y., & Shi, Q. (2023). Prediction model for labour dystocia occurring in the active phase. Journal of Obstetrics and Gynaecology, 43(1). https://doi.org/10.1080/01443615.2023.2174837
Nahaee, J., Abbas-Alizadeh, F., Mirghafourvand, M., & Mohammad-Alizadeh-Charandabi, S. (2020). Pre-and during-labour predictors of dystocia in the active phase of labour: A case-control study. BMC Pregnancy and Childbirth, 20(1). https://doi.org/10.1186/s12884-020-03113-5
Nguyen, M., Kozik, T. M., Bhattacharyya, M., & Oza, A. (2023). Association of Labor and Lactate Levels. Journal of Clinical Gynecology and Obstetrics, 12(3), 84–87. https://doi.org/10.14740/jcgo912
Niemczyk, N. A., Ren, D., & Stapleton, S. R. (2022). Associations between prolonged second stage of labor and maternal and neonatal outcomes in freestanding birth centers: a retrospective analysis. BMC Pregnancy and Childbirth, 22(1). https://doi.org/10.1186/s12884-022-04421-8
Olofsson, P. (2023). Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility. In American Journal of Obstetrics and Gynecology (Vol. 228, Issue 5, pp. S1222–S1240). Elsevier Inc. https://doi.org/10.1016/j.ajog.2022.07.001
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. In BMJ (Vol. 372). BMJ Publishing Group. https://doi.org/10.1136/bmj.n71
Pospiech, K., & Czajkowski, K. (2020). Amniotic Fluid Lactate Level as a Diagnostic Tool for Prolonged Labour. Journal of Mother and Child, 24(3), 3–7. https://doi.org/10.34763/jmotherandchild.20202403.2027.d-20-00011
Raa, A., Sunde, G. A., Bolann, B., Kvåle, R., Bjerkvig, C., Eliassen, H. S., Wentzel-Larsen, T., & Heltne, J. K. (2020). Validation of a point-of-care capillary lactate measuring device (Lactate Pro 2). Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28(1). https://doi.org/10.1186/s13049-020-00776-z
Rosen, H., & Yogev, Y. (2023). Assessment of uterine contractions in labor and delivery. In American Journal of Obstetrics and Gynecology (Vol. 228, Issue 5, pp. S1209–S1221). Elsevier Inc. https://doi.org/10.1016/j.ajog.2022.09.003
Salameh, J. P., Bossuyt, P. M., McGrath, T. A., Thombs, B. D., Hyde, C. J., MacAskill, P., Deeks, J. J., Leeflang, M., Korevaar, D. A., Whiting, P., Takwoingi, Y., Reitsma, J. B., Cohen, J. F., Frank, R. A., Hunt, H. A., Hooft, L., Rutjes, A. W. S., Willis, B. H., Gatsonis, C., … McInnes, M. D. F. (2020). Preferred reporting items for systematic review and meta-analysis of diagnostic test accuracy studies (PRISMA-DTA): Explanation, elaboration, and checklist. In The BMJ (Vol. 370, Issue 12). BMJ Publishing Group. https://doi.org/10.1136/bmj.m2632
Shazly, S. A., Borah, B. J., Ngufor, C. G., Torbenson, V. E., Theiler, R. N., & Famuyide, A. O. (2022). Impact of labor characteristics on maternal and neonatal outcomes of labor: A machine-learning model. PLoS ONE, 17(8), 1–13. https://doi.org/10.1371/journal.pone.0273178
Turnbull, D., Chugh, R., & Luck, J. (2023). Systematic-narrative hybrid literature review: A strategy for integrating a concise methodology into a manuscript. Social Sciences and Humanities Open, 7(1). https://doi.org/10.1016/j.ssaho.2022.100381
Vallely, L. H., Shalit, A., Nguyen, R., Althabe, F., Pingray, V., Bonet, M., Armari, E., Bohren, M., Homer, C., & Vogel, J. P. (2023). Intrapartum Care Measures and Indicators for Monitoring The Implementation of WHO Recommendations for a Positive Childbirth Experience: a Scoping Review. BMJ Open, 13. https://doi.org/10.1136/bmjopen-2022-069081
Waldenström, U., & Ekéus, C. (2017). Risk of labor dystocia increases with maternal age irrespective of parity: a population-based register study. Acta Obstetricia et Gynecologica Scandinavica, 96(9), 1063–1069. https://doi.org/10.1111/aogs.13167
Wang, L., Wang, H., Jia, L., Qing, W., Li, F., & Zhou, J. (2020). The Impact of Stage of Labor on Adverse Maternal and Neonatal Outcomes in Multiparous Women: A Retrospective Cohort Study. BMC Pregnancy and Childbirth, 20(1), 1–11. https://doi.org/10.1186/s12884-020-03286-z
Wiberg-Itzel, E. (2022). Amniotic fluid lactate (AFL): a new predictor of labor outcome in dystocic deliveries. Journal of Maternal-Fetal and Neonatal Medicine, 35(25), 7306–7311. https://doi.org/10.1080/14767058.2021.1946790
Wiberg-Itzel, E., Pembe, A. B., Järnbert-Pettersson, H., Norman, M., Wihlbäck, A. C., Hoesli, I., Bernasconi, M. T., Azria, E., Åkerud, H., & Darj, E. (2016). Lactate in amniotic fluid: Predictor of labor outcome in oxytocin-augmentedprimiparas’ deliveries. PLoS ONE, 11(10). https://doi.org/10.1371/journal.pone.0161546
Wray, S., Alruwaili, M., & Prendergast, C. (2021). Hypoxia and labour. Reproduction Special Review. https://doi.org/10.1530/REP
Young, C., Bhattacharya, S., Woolner, A., Ingram, A., Smith, N., Raja, E. A., & Black, M. (2023). Maternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women. BMC Pregnancy and Childbirth, 23(1). https://doi.org/10.1186/s12884-023-05733-z
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